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Bionas in-vitro Systems- excellence in live cell analysis

Bionas® specializes in instruments and services for real-time and label-free cell-based assays.

The Bionas® 2500 analyzing system is a 6 channel system for the simultaneous monitoring of oxygen consumption, acidification and cellular impedance (adhesion/confluence). The instrument provides real-time data about the metabolic activity of cells, including regeneration effects. Adherent, primary or suspension cells can be analyzed for applications in toxicology, oncology and drug discovery.

Bionas® also offers GLP laboratory service to its customers


Product News:

Bionas® 9600 adcon reader -Impedance-based cellular analysis

Real-time and label-free cellular analysis for applications in

  • compound mediated toxicity
  • chemo- and radiosensitivity testing in oncology
  • drug discovery, drug profiling
  • GPCR assays
  • standardization and optimization of cell culture
  • quality control of cells

The impedance technology allows non-invasive, label-free monitoring of dynamic cellular events in real-time for screening applications and laboratory research. The Bionas® 9600 adcon reader technology allows faster classification of leads and reduces time to market.

Instrument key features:

  • label-free
  • real-time data acquisition
  • continuous measurement for seconds up to days
  • simple handling
  • easy upgrade to increase throughput in cell culture labs
  • HTS compatible

 

For more information about the Bionas® 9600 adcon reader visit the product page

Examples of real-time data generated with Bionas® 9600 adcon reader:

 

 

Fig 1: Different numbers of V79 cells were initially seeded and proliferation was monitored for 72h using impedance technology.

 

 

 

 

 

Fig. 2: Carbachol-induced activation of native Gq-coupled mAChR of TE671 Cells and antagonistic effect of atropine and pirenzepine

 

 

Real-time monitoring of cell impedance has been validated through Bionas® 2500 analyzing system in many applications.

The Bionas® 9600 adcon reader is intended for research use only, not for diagnostic applications.